Its causative agent is Listeria monocytogenes.
It has 16 serotypes on the basis of flageller or somatic Ag.
Virulent strain multiply in macrophages and monocytes and produce
Lesteriolysin O (major virulent factor). It can grow on wide range
of pH i.e. from 4.5 to 9.6. Organism is susceptible to almost all
common disinfectants.
Sources of Infection:
Organism is common in environment and mammals, birds, insects, and
fish are susceptible. Organism can be isolated from animal fecal
material, soil, silage, water trough, animal feed, walls and floor of farm,
animal itself can be source of Listeria. |
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Transmission:
Lambs can ingest contaminated feed, or it may be congenital disease.
Clinical signs:
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Flock depressed
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Fever (104-107 oF)
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In-coordination
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Head deviation (tilting)
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Walking in circles
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Facial paralysis
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Dropping of ears
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Lips paralysis
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Third eye lid paralysis
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Panopthalmitis
(pus in anterior chamber of one or both eyes)
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Prehension and mastication
become slow
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Drooling of saliva
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Food hanging from mouth
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Abortion in pregnant animal
Septicemic Listeriosis:
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Depression, weakness, fever, diarrhea, death within 12 hours.
Treatment:
Chlorotetracyclin 10 mg per Kg body weight. Penicillin 44000 IU/Kg
body weight intramuscularly for 7 days or may continue upto 14 days.
Fluid therapy as supportive therapy.
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